Thought this possibly could be helpful to some of those actively seeking out pain medications and their relationship and strength ratio compared to other a lot more well known meds. The numbers & rates listed below are relative to the following; Analgesic/opioid Strength when compared to ********, Equivalent dose (10 mg ********), Bioavailability, Half-life of active metabolites (hours)
Aspirin (non-opioid) 1/360 no equivalent dose total 3.1–9
Diflunisal (NSAID, non-opioid) 1/160 1600 mg 80–90% 8–12
Dextroprop***phene[3] 1/13 to 1/20 130–200 mg
Codeine 1/10 100 mg ≈90% 2.5–3 (C6G 1.94;[4] ******** 2–3)
Tramadol 1/10 100 mg 68–72% 5.5–7 (≈9)[clarification needed]
Tapentadol 1/10 100 mg 95%
Alphaprodine 1/4–1/6 40–60 mg
Pethidine (meperidine *****chloride) 1/3 28 mg 50–60% 3–5
hydrocodone 1 10 mg ≥80% 3.8–6
******** (oral) (1) (10 mg) ≈25% 2–3
oxycodone 1.5–2.0 5.0–6.7 mg ≤87% 3–4.5
******** (IV/IM) 3 3.33 mg 100% 2–3
Methadone (acute) [6][7] 3–4 2.5–3.33 mg 40–90% 15–60
Dia******** (Heroin; IV/IM)[8] 4–5 2–2.5 mg 100% <0.6
hydromorphone[9] 5 2 mg 30–35% 2–3
hydromorphone 7 1.4 mg 10% 7.25–9.43
Methadone (chronic) [7] 7.5 1.35 mg 40–90% 15–60
7-*****xymitragynine 17 ≈.six mg
Buprenorphine[3][dead link] 40 0.25 mg 35–40% (sublingual) 20–70, mean thirty-seven
Fentanyl 50–100 0.1–0.2 mg 33% (oral); 92% (transdermal) 0.04 (IV); 7 (transdermal)
Di*****etorphine [notes 2] 1000–12,000 20–40 µg
Carfentanil [notes 2][10] 10,000–100,000 0.1–1.0 μg 7.7